An opportunist senator sends off the grandson of the first chimp astronaut, Ham III, into space. Ham III must focus on the mission to rid a far-away planet of their wicked leader. Luckily, Ham III is able to complete the mission with the help of two of his peers! Andy Samberg, Stanley Tucci, Jeff Daniels and Cheryl Hines star in this animated film opening July 18th, 2008.